STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECTD4HECT domain E3 ubiquitin protein ligase 4. (4428 aa)    
Predicted Functional Partners:
EVC
Ellis van creveld syndrome protein 1.
   
 0.490
RANBP2
E3 SUMO-protein ligase RanBP2.
   
 0.476
GGA3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3.
   
 
 0.474
SLC17A3
Solute carrier family 17 member 3.
    
 
 0.422
ZFAND4
AN1-type zinc finger and ubiquitin domain-containing protein 1.
    
 0.421
CDSN
Corneodesmosin.
      
 0.410
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.