STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHC3SHC-transforming protein 3. (583 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-binding protein 2.
   
 0.987
EGFR
Epidermal growth factor receptor.
    
 0.978
ERBB2
Receptor tyrosine-protein kinase erbB-2.
    
 0.974
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.974
IGF1R
Insulin like growth factor 1 receptor.
    
 0.971
ERBB3
Receptor tyrosine-protein kinase erbB-3.
    
 0.969
ERBB4
Receptor tyrosine-protein kinase erbB-4.
    
 0.969
SOS2
SOS Ras/Rho guanine nucleotide exchange factor 2.
   
 0.967
NTRK3
Neurotrophic tyrosine kinase, receptor type 3.
   
 0.965
MET
MET proto-oncogene, receptor tyrosine kinase.
   
 0.963
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.