STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIRT1NAD+-dependent protein deacetylase sirtuin 1. (738 aa)    
Predicted Functional Partners:
FOXO3
Forkhead box protein O3.
    
 0.997
FOXO1
Forkhead box protein O1.
    
 0.995
PPARGC1A
Alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha.
   
 0.992
TP53
Tumor protein p53.
    
 0.987
NAMPT
Nicotinamide phosphoribosyltransferase.
   
 
 0.985
PPARG
Peroxisome proliferator activated receptor gamma.
    
 0.979
NMNAT2
Nicotinamide mononucleotide adenylyltransferase.
   
 0.964
NMNAT3
Nicotinamide mononucleotide adenylyltransferase.
   
 0.960
NMNAT1
Nicotinamide mononucleotide adenylyltransferase.
   
 0.959
RRP8
Ribosomal RNA processing 8, methyltransferase, homolog (yeast).
    
 0.956
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
Server load: low (18%) [HD]