STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTHFD2LMethylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase. (347 aa)    
Predicted Functional Partners:
GART
annotation not available
  
 
 0.999
SHMT2
Serine hydroxymethyltransferase 2.
  
 0.990
TYMS
Thymidylate synthetase.
  
 
 0.989
MTHFR
Methylenetetrahydrofolate reductase (NADPH).
    
 0.985
AMT
Aminomethyltransferase.
  
 
 0.983
SHMT1
Serine hydroxymethyltransferase 1.
  
 0.983
MTFMT
Mitochondrial methionyl-tRNA formyltransferase.
  
 
 0.978
MTHFD1L
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like.
 
 
0.976
MTHFD1
C-1-tetrahydrofolate synthase, cytoplasmic.
  
 
0.972
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.
  
 
 0.972
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.