STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNA2Cyclin A2. (432 aa)    
Predicted Functional Partners:
CDK2
Cyclin dependent kinase 2.
 
 
 0.999
CDC6
Cell division control protein 6.
   
 0.999
CENPA
Histone H3-like centromeric protein A.
   
 0.999
CDK1
Cyclin dependent kinase 1.
 
 
 0.999
AURKB
Aurora kinase B.
   
 
 0.999
CDK4
Cyclin dependent kinase 4.
 
 
 0.998
CDK6
Cyclin dependent kinase 6.
 
 
 0.997
CDC20
Cell division cycle 20, cofactor of APC complex.
   
 0.995
E2F1
E2F transcription factor 1.
   
 0.995
SKP2
S-phase kinase associated protein 2.
   
 0.993
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.