STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUV39H2[histone H3]-lysine9 N-trimethyltransferase SUV39H. (350 aa)    
Predicted Functional Partners:
SIRT1
NAD+-dependent protein deacetylase sirtuin 1.
   
 0.921
RRP8
Ribosomal RNA processing 8, methyltransferase, homolog (yeast).
   
 0.898
CBX3
Chromobox protein 3.
   
0.887
SUZ12
SUZ12 polycomb repressive complex 2 subunit.
   
 0.868
EED
Embryonic ectoderm development.
   
 0.851
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
   
0.850
DDB1
Damage specific DNA binding protein 1.
    
 0.830
H3-3A
H3 histone, family 3B.
   
 0.822
CBX5
Chromobox protein 5.
   
 0.818
CBX1
Chromobox protein 1.
   
 0.801
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.