STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TLR8Toll like receptor 8. (997 aa)    
Predicted Functional Partners:
UNC93B1
Unc-93 homolog B1 (C. elegans).
    
 0.948
MYD88
Myeloid differentiation primary response protein MyD88.
   
 0.941
TLR9
Toll like receptor 9.
    
0.857
CD4
T-cell surface glycoprotein CD4.
   
 0.772
LY96
Lymphocyte antigen 96.
   
 0.726
TRAF6
TNF receptor associated factor 6.
   
 0.717
IRF7
Interferon regulatory factor 7.
   
 
 0.699
LY86
Lymphocyte antigen 86.
   
 0.677
IRF3
Interferon regulatory factor 3.
   
 
 0.660
IFNG
Interferon gamma.
   
  
 0.656
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.