STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOT1L[histone H3]-lysine79 N-trimethyltransferase. (1541 aa)    
Predicted Functional Partners:
MLLT10
Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10.
    
 
 0.955
ENSEASP00005006851
Histone H3.1-like.
   
 0.903
ENSEASP00005007153
Histone H3.1.
   
 0.903
MLLT6
MLLT6, PHD finger domain containing.
    
 
 0.816
H3-3A
H3 histone, family 3B.
   
 0.811
ENSEASP00005007144
annotation not available
   
 0.778
ENSEASP00005025486
annotation not available
   
   0.721
CAMKMT
Calmodulin-lysine N-methyltransferase.
     
 0.720
MLLT3
MLLT3, super elongation complex subunit.
    
 
 0.680
SETD2
[histone H3]-dimethyl-L-lysine36 N-methyltransferase.
   
 
 0.658
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.