STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APLP2Amyloid beta precursor like protein 2. (763 aa)    
Predicted Functional Partners:
BACE1
Beta-site APP-cleaving enzyme 1 (memapsin 2).
    
 0.897
PIANP
PILR alpha associated neural protein.
      
 0.761
SORL1
Sortilin related receptor 1.
    
 0.743
SYT11
Synaptotagmin 11.
   
 
 0.717
PSEN1
Presenilin 1.
    
 
 0.716
NCSTN
Nicastrin.
    
 0.705
APBB1
Amyloid beta A4 precursor protein-binding family B member 1.
    
 0.695
BACE2
Beta-site APP-cleaving enzyme 2 (memapsin 1).
    
 0.682
APH1B
Aph-1 homolog B, gamma-secretase subunit.
    
 0.639
NAALADL2
N-acetylated alpha-linked acidic dipeptidase like 2.
   
  
 0.636
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.