STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1609 aa)    
Predicted Functional Partners:
CDC42
Cell division control protein 42.
    
 0.807
PDCL
Phosducin like.
      
 0.712
RAC2
Rac family small GTPase 2.
    
 0.693
GMIP
GEM interacting protein.
    
 
 0.691
GOLGB1
Golgin subfamily B member 1.
      
 0.653
RHOG
Ras homolog gene family, member G.
    
 0.637
DOCK2
Dedicator of cytokinesis protein 2.
   
 
 0.611
PTEN
Phosphatase and tensin homolog.
     
 0.604
ELMO2
Engulfment and cell motility protein 2.
      
 0.594
PPFIA2
PTPRF interacting protein alpha 2.
   
  
 0.588
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.