STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purRPur operon repressor. (276 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.776
AKL94647.1
Glutamine amidotransferase class-I.
  
 
 0.776
purL
Phosphoribosylformylglycinamidine synthase PurL.
  
  
 0.760
gluM
UDP-N-acetylglucosamine pyrophosphorylase GluM; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
 
  
 0.743
ribP
Ribose-phosphate pyrophosphokinase RibP; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
 
  
 0.714
murC
UDP-N-acetylmuramate--L-alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.682
spoVG
Septation protein SpoVG; Could be involved in septation.
     
 0.671
tyrA
Prephenate dehydrogenase TyrA.
  
  
 0.575
AKL97141.1
Putative protein DUF1021.
 
     0.561
AKL94699.1
Transcriptional regulator.
  
   
 0.547
Your Current Organism:
Clostridium aceticum
NCBI taxonomy Id: 84022
Other names: ATCC 35044, C. aceticum
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