STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemZOxygen-independent coproporphyrinogen-III oxidase 2. (491 aa)    
Predicted Functional Partners:
aspS1
aspartyl-tRNA synthetase AspS; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
       0.815
AKL95186.1
Zn-dependent hydrolase.
       0.694
dtd
D-tyrosyl-tRNA(Tyr) deacylase Dtd; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family.
       0.671
relA
GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
    0.663
mtbA1
methylcobamide:CoM methyltransferase MtbA; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.650
apt
Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
  
 0.621
argS
arginyl-tRNA synthetase ArgS.
   
    0.579
AKL95177.1
Radical SAM domain-containing protein.
 
     0.573
AKL97123.1
Putative protein DUF1934.
   
    0.560
AKL93935.1
uroporphyrinogen-III decarboxylase; Belongs to the uroporphyrinogen decarboxylase family.
  
 
 0.527
Your Current Organism:
Clostridium aceticum
NCBI taxonomy Id: 84022
Other names: ATCC 35044, C. aceticum
Server load: low (30%) [HD]