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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polCDNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1431 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III subunit beta DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]
    
 0.951
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.942
holB
DNA polymerase III subunit delta'.
   
 0.921
holA
DNA polymerase III subunit delta.
    
 0.921
dnaE1
DNA polymerase III subunit alpha; Belongs to the DNA polymerase type-C family.
    
0.919
dnaE2
DNA polymerase III subunit alpha.
    
0.919
AKL95439.1
Glycosyl transferase, family 2.
     
 0.811
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.792
nusA
Transcription elongation protein NusA; Participates in both transcription termination and antitermination.
 
    0.759
AKL95435.1
Nucleic-acid-binding protein.
 
    0.691
Your Current Organism:
Clostridium aceticum
NCBI taxonomy Id: 84022
Other names: ATCC 35044, C. aceticum
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