STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polCDNA polymerase III PolC-type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1431 aa)    
Predicted Functional Partners:
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.948
dnaN
DNA polymerase III subunit beta DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...]
    
 0.938
holA
DNA polymerase III subunit delta.
    
 0.935
dnaE1
DNA polymerase III subunit alpha; Belongs to the DNA polymerase type-C family.
    
0.920
dnaE2
DNA polymerase III subunit alpha.
    
0.920
holB
DNA polymerase III subunit delta'.
   
 0.917
AKL95439.1
Glycosyl transferase, family 2.
     
 0.811
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.794
nusA
Transcription elongation protein NusA; Participates in both transcription termination and antitermination.
 
    0.725
AKL95441.1
Zinc metalloprotease.
  
    0.687
Your Current Organism:
Clostridium aceticum
NCBI taxonomy Id: 84022
Other names: ATCC 35044, C. aceticum
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