STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIUnannotated protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (413 aa)    
Predicted Functional Partners:
CJ218_03805
Unannotated protein.
 
 0.993
CJ218_05425
Unannotated protein.
 
 0.966
RsmB
Unannotated protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
    0.933
trmFO
Unannotated protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily.
  
  
 0.768
rny
Unannotated protein; Endoribonuclease that initiates mRNA decay.
 
   
 0.572
mnmA
Unannotated protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
 
  
 0.525
codY
Unannotated protein; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
       0.522
CJ218_03795
Unannotated protein; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
       0.485
CJ218_03800
Unannotated protein.
       0.475
guaA
Unannotated protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.454
Your Current Organism:
Gemella sanguinis
NCBI taxonomy Id: 84135
Other names: ATCC 700632, CCUG 37820, CIP 105929, G. sanguinis, Gemella sp. 2045-94, LMG 18986, LMG:18986, strain 2045-94
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.