STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dltDUnannotated protein. (388 aa)    
Predicted Functional Partners:
dltB
Unannotated protein; Belongs to the membrane-bound acyltransferase family.
 
 
 0.999
DltA
Unannotated protein.
 
  
 0.994
dltC
Unannotated protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
  
 0.984
acpP
Unannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
  
 0.697
GCA_001052115_01371
Unannotated protein.
  
     0.563
CJ218_02655
Unannotated protein.
  
     0.541
GCA_001052115_01447
Unannotated protein.
 
  
 0.468
mprF
Unannotated protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
   
 0.450
ftsH
Unannotated protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.437
hpt
Unannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
    0.415
Your Current Organism:
Gemella sanguinis
NCBI taxonomy Id: 84135
Other names: ATCC 700632, CCUG 37820, CIP 105929, G. sanguinis, Gemella sp. 2045-94, LMG 18986, LMG:18986, strain 2045-94
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.