STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDI74539.1Putative MFS transporter, AGZA family, xanthine/uracil permease. (454 aa)    
Predicted Functional Partners:
SDI83875.1
Phosphoribosylformylglycinamidine synthase.
  
  
 0.892
SDI20641.1
Uracil permease.
 
  
 0.668
SDI50074.1
O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain.
      0.646
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
  
 0.505
purE
5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).
  
    0.503
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.501
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.500
SDI68330.1
Lactate dehydrogenase.
    
 0.481
SDI74511.1
Uncharacterized protein YpuA, DUF1002 family.
       0.480
purM
Phosphoribosylformylglycinamidine cyclo-ligase.
  
    0.462
Your Current Organism:
Dolosicoccus paucivorans
NCBI taxonomy Id: 84521
Other names: ATCC BAA-56, CCUG 39307, CIP 106314, D. paucivorans, DSM 15742, Streptococcus sp. 2992-95, strain 2992-95
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