STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crtLLycopene beta cyclase. (417 aa)    
Predicted Functional Partners:
crtQ,
Zeta-carotene desaturase; Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'.
  
  
 0.933
crtH
Carotenoid isomerase.
  
 
 0.924
SYNW1393
Similar to zeta-carotene desaturase.
  
  
 0.916
crtR
Beta-carotene hydroxylase.
   
 
 0.909
SYNW1368
Possible beta-carotene ketolase.
   
 
 0.905
gyrA
DNA gyrase A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.773
SYNW2459
Conserved hypothetical protein (ORFG Synechococcus sp.).
  
   
 0.656
SYNW0930
Conserved hypothetical protein.
  
     0.635
SYNW0726
Hypothetical.
       0.550
SYNW0887
Possible oxidase.
  
 
 
 0.541
Your Current Organism:
Synechococcus sp. WH 8102
NCBI taxonomy Id: 84588
Other names: S. sp. WH 8102, Synechococcus sp. WH8102
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.