STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PYGO2Phosphomevalonate kinase. (453 aa)    
Predicted Functional Partners:
MVD
Diphosphomevalonate decarboxylase.
   
 
 0.747
UY3_01637
Isopentenyl-diphosphate Delta-isomerase 1.
   
 
 0.653
FDPS
Farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
   
 
 0.622
HMGCR
3-hydroxy-3-methylglutaryl coenzyme A reductase.
     
 0.541
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.488
HMGCS2
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.468
DHCR7
7-dehydrocholesterol reductase.
   
 
 0.440
UY3_12612
Squalene monooxygenase.
   
  
 0.435
UY3_15701
Squalene synthase.
   
 
 0.431
SC5D
Lathosterol oxidase; Belongs to the sterol desaturase family.
   
  
 0.407
Your Current Organism:
Chelonia mydas
NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle
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