TTC33 protein (Chelonia mydas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TTC33

Tetratricopeptide repeat protein 33. (325 aa)

Predicted Functional Partners:

LEO1

0.871

GET4

0.772

UY3_18659

0.658

STX5

0.639

UY3_05560

0.628

UY3_05255

0.628

UY3_08022

0.598

ASNA1

0.598

UY3_02130

0.583

CDC16

0.570

Your Current Organism:

Chelonia mydas

NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASNA1	GET4	M7BYR7	M7B529	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Golgi to ER traffic protein 4 like protein.	0.918
ASNA1	STX5	M7BYR7	M7BCC2	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Syntaxin-5; Belongs to the syntaxin family.	0.693
ASNA1	TTC33	M7BYR7	M7AXM3	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Tetratricopeptide repeat protein 33.	0.598
ASNA1	UY3_05255	M7BYR7	M7BI02	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	UV excision repair protein RAD23 like protein B.	0.771
ASNA1	UY3_05560	M7BYR7	M7BH68	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	UV excision repair protein RAD23 like protein A.	0.771
CDC16	TTC33	M7BJ38	M7AXM3	Cell division cycle protein 16 like protein.	Tetratricopeptide repeat protein 33.	0.570
CDC16	UY3_05255	M7BJ38	M7BI02	Cell division cycle protein 16 like protein.	UV excision repair protein RAD23 like protein B.	0.404
CDC16	UY3_05560	M7BJ38	M7BH68	Cell division cycle protein 16 like protein.	UV excision repair protein RAD23 like protein A.	0.404
CDC16	UY3_18659	M7BJ38	M7B7P7	Cell division cycle protein 16 like protein.	Telomerase protein component 1.	0.614
GET4	ASNA1	M7B529	M7BYR7	Golgi to ER traffic protein 4 like protein.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.918
GET4	TTC33	M7B529	M7AXM3	Golgi to ER traffic protein 4 like protein.	Tetratricopeptide repeat protein 33.	0.772
GET4	UY3_05255	M7B529	M7BI02	Golgi to ER traffic protein 4 like protein.	UV excision repair protein RAD23 like protein B.	0.762
GET4	UY3_05560	M7B529	M7BH68	Golgi to ER traffic protein 4 like protein.	UV excision repair protein RAD23 like protein A.	0.762
GET4	UY3_08022	M7B529	M7BA62	Golgi to ER traffic protein 4 like protein.	ATPase asna1.	0.918
LEO1	TTC33	M7CDS6	M7AXM3	RNA polymerase-associated protein LEO1.	Tetratricopeptide repeat protein 33.	0.871
LEO1	UY3_05255	M7CDS6	M7BI02	RNA polymerase-associated protein LEO1.	UV excision repair protein RAD23 like protein B.	0.547
LEO1	UY3_05560	M7CDS6	M7BH68	RNA polymerase-associated protein LEO1.	UV excision repair protein RAD23 like protein A.	0.547
LEO1	UY3_18659	M7CDS6	M7B7P7	RNA polymerase-associated protein LEO1.	Telomerase protein component 1.	0.968
STX5	ASNA1	M7BCC2	M7BYR7	Syntaxin-5; Belongs to the syntaxin family.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.693
STX5	TTC33	M7BCC2	M7AXM3	Syntaxin-5; Belongs to the syntaxin family.	Tetratricopeptide repeat protein 33.	0.639