MAP3K5 protein (Chelonia mydas) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MAP3K5

Mitogen-activated protein kinase kinase kinase 5. (1218 aa)

Predicted Functional Partners:

MAP2K3

0.972

MAP2K6

0.972

UY3_05911

0.928

PPP5C

0.917

DAB2IP

0.916

AKT2

0.913

NME8

0.815

UY3_19145

0.760

UY3_16551

0.631

UY3_16339

0.631

Your Current Organism:

Chelonia mydas

NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT2	MAP3K5	M7B852	M7BNY1	Non-specific serine/threonine protein kinase.	Mitogen-activated protein kinase kinase kinase 5.	0.913
AKT2	UY3_19145	M7B852	M7AV94	Non-specific serine/threonine protein kinase.	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	0.922
DAB2IP	MAP3K5	M7C2G1	M7BNY1	Disabled like protein 2-interacting protein.	Mitogen-activated protein kinase kinase kinase 5.	0.916
MAP2K3	MAP2K6	M7B7G2	M7CES5	Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	0.901
MAP2K3	MAP3K5	M7B7G2	M7BNY1	Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 5.	0.972
MAP2K3	NME8	M7B7G2	M7BDD2	Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	Thioredoxin domain-containing protein 3.	0.563
MAP2K6	MAP2K3	M7CES5	M7B7G2	Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	0.901
MAP2K6	MAP3K5	M7CES5	M7BNY1	Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase 5.	0.972
MAP2K6	NME8	M7CES5	M7BDD2	Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	Thioredoxin domain-containing protein 3.	0.563
MAP3K5	AKT2	M7BNY1	M7B852	Mitogen-activated protein kinase kinase kinase 5.	Non-specific serine/threonine protein kinase.	0.913
MAP3K5	DAB2IP	M7BNY1	M7C2G1	Mitogen-activated protein kinase kinase kinase 5.	Disabled like protein 2-interacting protein.	0.916
MAP3K5	MAP2K3	M7BNY1	M7B7G2	Mitogen-activated protein kinase kinase kinase 5.	Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	0.972
MAP3K5	MAP2K6	M7BNY1	M7CES5	Mitogen-activated protein kinase kinase kinase 5.	Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.	0.972
MAP3K5	NME8	M7BNY1	M7BDD2	Mitogen-activated protein kinase kinase kinase 5.	Thioredoxin domain-containing protein 3.	0.815
MAP3K5	PPP5C	M7BNY1	M7AVL9	Mitogen-activated protein kinase kinase kinase 5.	Serine/threonine-protein phosphatase.	0.917
MAP3K5	UY3_05911	M7BNY1	M7BG95	Mitogen-activated protein kinase kinase kinase 5.	Serine/threonine-protein kinase/endoribonuclease IRE2.	0.928
MAP3K5	UY3_16339	M7BNY1	M7BED8	Mitogen-activated protein kinase kinase kinase 5.	Death domain-associated protein 6.	0.631
MAP3K5	UY3_16551	M7BNY1	M7BDS8	Mitogen-activated protein kinase kinase kinase 5.	DnaJ like protein subfamily C member 10.	0.631
MAP3K5	UY3_19145	M7BNY1	M7AV94	Mitogen-activated protein kinase kinase kinase 5.	Dual specificity mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily.	0.760
NME8	MAP2K3	M7BDD2	M7B7G2	Thioredoxin domain-containing protein 3.	Dual specificity mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	0.563