STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRAF6TNF receptor-associated factor 6. (344 aa)    
Predicted Functional Partners:
TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1.
   
 0.996
IRAK4
Interleukin-1 receptor-associated kinase 4.
   
 0.990
TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3.
    
 0.989
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
0.988
TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2.
    
 0.987
ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway.
    
 0.984
TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein.
   
 0.976
TICAM1
TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines.
   
 0.964
UY3_08114
Interferon regulatory factor 3.
   
 0.962
UY3_10091
Mitogen-activated protein kinase kinase kinase 7.
   
 0.953
Your Current Organism:
Chelonia mydas
NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.