SNX12 protein (Chelonia mydas) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

SNX12

Sorting nexin-12. (529 aa)

Predicted Functional Partners:

VPS35

0.934

VPS26B

0.879

VPS26A

0.872

VPS29

0.721

UY3_02103

0.712

UY3_10471

0.696

UY3_06567

0.657

HGS

0.529

SNX27

0.497

UY3_04891

0.471

Your Current Organism:

Chelonia mydas

NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HGS	SNX12	M7BK97	M7BTR2	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Sorting nexin-12.	0.529
HGS	VPS35	M7BK97	M7BFE1	Hepatocyte growth factor-regulated tyrosine kinase substrate.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.564
SNX12	HGS	M7BTR2	M7BK97	Sorting nexin-12.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.529
SNX12	SNX27	M7BTR2	M7ARK7	Sorting nexin-12.	Sorting nexin-27.	0.497
SNX12	UY3_02103	M7BTR2	M7C7V4	Sorting nexin-12.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.712
SNX12	UY3_04891	M7BTR2	M7BL25	Sorting nexin-12.	Sorting nexin-17.	0.471
SNX12	UY3_06567	M7BTR2	M7BGA3	Sorting nexin-12.	Ubiquitin carboxyl-terminal hydrolase 10; Belongs to the peptidase C19 family.	0.657
SNX12	UY3_10471	M7BTR2	M7B5I6	Sorting nexin-12.	Protein wntless like protein.	0.696
SNX12	VPS26A	M7BTR2	M7BRQ2	Sorting nexin-12.	Vacuolar protein sorting-associated protein 26A.	0.872
SNX12	VPS26B	M7BTR2	M7AUE4	Sorting nexin-12.	Vacuolar protein sorting-associated protein 26B.	0.879
SNX12	VPS29	M7BTR2	M7BYF5	Sorting nexin-12.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.721
SNX12	VPS35	M7BTR2	M7BFE1	Sorting nexin-12.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.934
SNX27	SNX12	M7ARK7	M7BTR2	Sorting nexin-27.	Sorting nexin-12.	0.497
SNX27	UY3_02103	M7ARK7	M7C7V4	Sorting nexin-27.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.504
SNX27	UY3_04891	M7ARK7	M7BL25	Sorting nexin-27.	Sorting nexin-17.	0.429
SNX27	VPS26A	M7ARK7	M7BRQ2	Sorting nexin-27.	Vacuolar protein sorting-associated protein 26A.	0.935
SNX27	VPS26B	M7ARK7	M7AUE4	Sorting nexin-27.	Vacuolar protein sorting-associated protein 26B.	0.776
SNX27	VPS29	M7ARK7	M7BYF5	Sorting nexin-27.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.707
SNX27	VPS35	M7ARK7	M7BFE1	Sorting nexin-27.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.827
UY3_02103	SNX12	M7C7V4	M7BTR2	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Sorting nexin-12.	0.712