STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM17Disintegrin and metalloproteinase domain-containing protein 17. (731 aa)    
Predicted Functional Partners:
TIMP3
Metalloproteinase inhibitor 3.
    
 0.918
UY3_08390
Neurogenic locus notch like protein 2.
    
 0.909
NOTCH1
Neurogenic locus notch like protein 1.
    
 0.906
NOTCH3
Epoxide hydrolase 4.
     
  0.900
TIMP2
Metalloproteinase inhibitor 2.
    
 0.673
UY3_13366
Tumor necrosis factor receptor superfamily member 16.
     
 0.624
FURIN
Furin; Belongs to the peptidase S8 family.
     
 0.622
UY3_11583
Nicastrin.
    
 
 0.608
SUMO1
Small ubiquitin-related modifier.
      
 0.575
TGFA
Protransforming growth factor alpha.
   
 
 0.549
Your Current Organism:
Chelonia mydas
NCBI taxonomy Id: 8469
Other names: C. mydas, Chelonia midas, Chelonia mydas caranigra, Green sea turtle, Testudo mydas, green seaturtle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.