STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFB06309.1uroporphyrinogen-III synthase. (491 aa)    
Predicted Functional Partners:
SFB06290.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 0.999
SFB06364.1
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase.
 
 
 0.998
SFB06081.1
Cobalt-factor II C20-methyltransferase; Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway.
 
 
 0.987
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
 
 0.982
SFB06027.1
Cobalt-precorrin 3 C17-methyltransferase.
 
 
0.982
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.981
SFB06006.1
precorrin-6A reductase.
 
 
 0.981
SFB06045.1
Cobalt-precorrin 5A acetaldehyde-lyase.
 
  
 0.969
SFB06219.1
Anaerobic cobaltochelatase.
 
 
 0.965
Your Current Organism:
Clostridium frigidicarnis
NCBI taxonomy Id: 84698
Other names: ATCC BAA-154, C. frigidicarnis, DSM 12271, strain SPL77A
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