node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFA84104.1 | SFA92020.1 | SAMN04488528_100475 | SAMN04488528_100652 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.815 |
SFA84104.1 | SFA93558.1 | SAMN04488528_100475 | SAMN04488528_1006161 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.462 |
SFA84104.1 | SFB33519.1 | SAMN04488528_100475 | SAMN04488528_103043 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | 0.643 |
SFA84104.1 | SFB46672.1 | SAMN04488528_100475 | SAMN04488528_10784 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 5-methyltetrahydrofolate--homocysteine methyltransferase. | 0.462 |
SFA84104.1 | polA | SAMN04488528_100475 | SAMN04488528_102831 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.891 |
SFA84104.1 | ribBA | SAMN04488528_100475 | SAMN04488528_101254 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.916 |
SFA92020.1 | SFA84104.1 | SAMN04488528_100652 | SAMN04488528_100475 | Dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.815 |
SFA92020.1 | SFB33519.1 | SAMN04488528_100652 | SAMN04488528_103043 | Dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | 0.772 |
SFA92020.1 | SFB35500.1 | SAMN04488528_100652 | SAMN04488528_103318 | Dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | PEP-utilising enzyme, mobile domain. | 0.512 |
SFA92020.1 | nadE | SAMN04488528_100652 | SAMN04488528_1004166 | Dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.792 |
SFA92020.1 | ribBA | SAMN04488528_100652 | SAMN04488528_101254 | Dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.976 |
SFA93558.1 | SFA84104.1 | SAMN04488528_1006161 | SAMN04488528_100475 | Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.462 |
SFA93558.1 | SFB23125.1 | SAMN04488528_1006161 | SAMN04488528_101946 | Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 0.947 |
SFA93558.1 | SFB33519.1 | SAMN04488528_1006161 | SAMN04488528_103043 | Methionine synthase I (cobalamin-dependent), methyltransferase domain. | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | 0.902 |
SFA93558.1 | SFB46672.1 | SAMN04488528_1006161 | SAMN04488528_10784 | Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 5-methyltetrahydrofolate--homocysteine methyltransferase. | 0.956 |
SFA93558.1 | cinA | SAMN04488528_1006161 | SAMN04488528_103611 | Methionine synthase I (cobalamin-dependent), methyltransferase domain. | Competence/damage-inducible protein cinA; Belongs to the CinA family. | 0.461 |
SFB23125.1 | SFA93558.1 | SAMN04488528_101946 | SAMN04488528_1006161 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.947 |
SFB23125.1 | SFB33519.1 | SAMN04488528_101946 | SAMN04488528_103043 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | NUDIX domain-containing protein; Belongs to the Nudix hydrolase family. | 0.774 |
SFB23125.1 | SFB35500.1 | SAMN04488528_101946 | SAMN04488528_103318 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | PEP-utilising enzyme, mobile domain. | 0.968 |
SFB23125.1 | SFB46672.1 | SAMN04488528_101946 | SAMN04488528_10784 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 5-methyltetrahydrofolate--homocysteine methyltransferase. | 0.947 |