STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFB39405.1Biotin-requiring enzyme. (124 aa)    
Predicted Functional Partners:
SFB39426.1
Acetyl-CoA carboxylase, carboxyltransferase component.
 
 0.999
accD-2
acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 0.993
birA
Bifunctional ligase/repressor BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
  
 0.987
SFB07600.1
Amino acid adenylation domain-containing protein; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.982
SFB36565.1
Oxaloacetate decarboxylase, alpha subunit.
 
 
 0.982
SFA77276.1
acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.970
SFB23125.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
  
 0.960
SFB39415.1
Oxaloacetate decarboxylase, gamma chain.
  
 0.954
SFB44811.1
enoyl-CoA hydratase.
  
 0.911
SFB39990.1
Phosphopantetheine attachment site.
  
 
 0.898
Your Current Organism:
Clostridium frigidicarnis
NCBI taxonomy Id: 84698
Other names: ATCC BAA-154, C. frigidicarnis, DSM 12271, strain SPL77A
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