Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ltxDLeukotoxin export protein LtxD. (393 aa)    
Predicted Functional Partners:
apxIB
Toxin RTX-I translocation ATP-binding protein.
 
 0.995
ARQ46873.1
Hypothetical protein.
 
     0.914
bepC
Outer membrane efflux protein BepC.
 
 
 0.892
ARQ46871.1
Hypothetical protein.
 
  
 0.846
macB
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
  
 0.816
ltxA_1
Leukotoxin.
 
  
 0.791
cya
Bifunctional hemolysin/adenylate cyclase.
 
  
 0.791
ltxA_2
Leukotoxin.
 
  
 0.788
ARQ46872.1
Putative signaling protein.
 
  
 0.755
ltxA_3
Leukotoxin.
 
    0.692
Your Current Organism:
Oxalobacter formigenes
NCBI taxonomy Id: 847
Other names: ATCC 35274, CIP 106513, O. formigenes, strain OxB
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