| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acrA | acrB | BRW83_2146 | BRW83_2147 | Multidrug efflux pump subunit AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Multidrug efflux pump subunit AcrB. | 0.996 |
| acrA | macB | BRW83_2146 | BRW83_2278 | Multidrug efflux pump subunit AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.996 |
| acrA | oprM_3 | BRW83_2146 | BRW83_2148 | Multidrug efflux pump subunit AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Outer membrane protein OprM. | 0.990 |
| acrA | ttgR | BRW83_2146 | BRW83_2145 | Multidrug efflux pump subunit AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | HTH-type transcriptional regulator TtgR. | 0.500 |
| acrB | acrA | BRW83_2147 | BRW83_2146 | Multidrug efflux pump subunit AcrB. | Multidrug efflux pump subunit AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.996 |
| acrB | macB | BRW83_2147 | BRW83_2278 | Multidrug efflux pump subunit AcrB. | Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.472 |
| acrB | oprM_3 | BRW83_2147 | BRW83_2148 | Multidrug efflux pump subunit AcrB. | Outer membrane protein OprM. | 0.998 |
| acrB | ttgR | BRW83_2147 | BRW83_2145 | Multidrug efflux pump subunit AcrB. | HTH-type transcriptional regulator TtgR. | 0.453 |
| barA_4 | cph2_1 | BRW83_1652 | BRW83_0620 | Signal transduction histidine-protein kinase BarA. | Phytochrome-like protein cph2. | 0.996 |
| barA_4 | cph2_4 | BRW83_1652 | BRW83_1729 | Signal transduction histidine-protein kinase BarA. | Phytochrome-like protein cph2. | 0.826 |
| barA_4 | macB | BRW83_1652 | BRW83_2278 | Signal transduction histidine-protein kinase BarA. | Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.628 |
| barA_4 | rpfC_2 | BRW83_1652 | BRW83_1602 | Signal transduction histidine-protein kinase BarA. | Sensory/regulatory protein RpfC. | 0.997 |
| barA_4 | ttgR | BRW83_1652 | BRW83_2145 | Signal transduction histidine-protein kinase BarA. | HTH-type transcriptional regulator TtgR. | 0.405 |
| cph2_1 | barA_4 | BRW83_0620 | BRW83_1652 | Phytochrome-like protein cph2. | Signal transduction histidine-protein kinase BarA. | 0.996 |
| cph2_1 | cph2_4 | BRW83_0620 | BRW83_1729 | Phytochrome-like protein cph2. | Phytochrome-like protein cph2. | 0.863 |
| cph2_1 | macB | BRW83_0620 | BRW83_2278 | Phytochrome-like protein cph2. | Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.431 |
| cph2_1 | rpfC_2 | BRW83_0620 | BRW83_1602 | Phytochrome-like protein cph2. | Sensory/regulatory protein RpfC. | 0.997 |
| cph2_1 | ttgR | BRW83_0620 | BRW83_2145 | Phytochrome-like protein cph2. | HTH-type transcriptional regulator TtgR. | 0.402 |
| cph2_4 | barA_4 | BRW83_1729 | BRW83_1652 | Phytochrome-like protein cph2. | Signal transduction histidine-protein kinase BarA. | 0.826 |
| cph2_4 | cph2_1 | BRW83_1729 | BRW83_0620 | Phytochrome-like protein cph2. | Phytochrome-like protein cph2. | 0.863 |