STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFR04939.14-hydroxy 2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (340 aa)    
Predicted Functional Partners:
SFR04944.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
 0.999
SFR23835.1
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
 
 0.999
SFR04949.1
2-keto-4-pentenoate hydratase.
 
 
 0.992
SFQ95196.1
Acetyl/propionyl-CoA carboxylase, alpha subunit.
  
 0.962
SFR04494.1
2-oxo-3-hexenedioate decarboxylase.
 
 
 0.956
SFR23833.1
2-keto-4-pentenoate hydratase.
 
 
 0.956
SFR04931.1
4,5:9,10-diseco-3-hydroxy-5,9, 17-trioxoandrosta-1(10),2-diene-4-oate hydrolase.
 
 
  0.918
SFR04926.1
3,4-dihydroxy-9,10-secoandrosta-1,3, 5(10)-triene-9,17-dione 4,5-dioxygenase.
 
   
 0.914
SFR04934.1
3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9, 17-dione monooxygenase.
 
  0.883
SFR04953.1
3-oxo-5alpha-steroid 4-dehydrogenase.
 
 
 0.857
Your Current Organism:
Lentzea waywayandensis
NCBI taxonomy Id: 84724
Other names: ATCC 51594, DSM 44232, IFO 14970, JCM 9114, L. waywayandensis, NBRC 14970, NRRL B-16159, Saccharothrix waywayandensis, strain LL-37Z-15
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.