STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MDM4MDM4, p53 regulator. (477 aa)    
Predicted Functional Partners:
MDM2
E3 ubiquitin-protein ligase Mdm2.
    
0.999
TP53
Tumor protein p53.
   
 0.999
RPS27A
Ubiquitin-small subunit ribosomal protein S27Ae.
    
 0.923
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.884
USP7
Ubiquitin carboxyl-terminal hydrolase 7.
    
 0.883
RPL11
Large subunit ribosomal protein L11e.
    
 
 0.844
ATM
ATM serine/threonine kinase.
   
 0.833
DAXX
Death domain associated protein.
    
 0.789
CHEK2
Serine/threonine-protein kinase CHEK2.
    
 0.772
CSNK1A1
Casein kinase 1 alpha 1.
    
 
 0.731
Your Current Organism:
Chrysemys picta
NCBI taxonomy Id: 8478
Other names: C. picta bellii, Chrysemys picta bellii, Chrysemys picta subsp. bellii, western painted turtle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.