STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPC25Kinetochore protein Spc25. (269 aa)    
Predicted Functional Partners:
NUF2
Kinetochore protein Nuf2.
   
 0.999
NDC80
Kinetochore NDC80-like protein.
   
 0.999
SPC24
Kinetochore protein Spc24.
   
 0.998
DSN1
Kinetochore-associated DSN1-like protein.
   
 0.992
NSL1
Kinetochore-associated NSL1-like protein.
   
 0.991
BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1.
   
 0.989
MIS12
MIS12-like protein.
    
 0.989
BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta.
   
 0.985
ZWINT
ZW10 interactor.
   
 0.982
NNF1
Nnf1 protein.
   
  0.969
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.