STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGTAngiotensinogen; Belongs to the serpin family. (474 aa)    
Predicted Functional Partners:
AGTR2
Type-2 angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.998
ACE
Angiotensin-converting enzyme.
    
 0.968
ACE2
Angiotensin-converting enzyme.
    
 0.924
ATP6AP2
Renin receptor.
   
 0.844
REN
Renin; Belongs to the peptidase A1 family.
    
 0.832
TMEM27
Collectrin.
    
 0.829
TAC1
Protachykinin-1.
     
 0.822
EDNRA
Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.804
AGTRAP
Type-1 angiotensin II receptor-associated protein.
      
 0.782
NPEPPS
Aminopeptidase.
  
 0.762
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.