STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFX6DNA-binding protein RFX6 isoform B. (944 aa)    
Predicted Functional Partners:
ATR
Serine/threonine-protein kinase ATR isoform A; Belongs to the PI3/PI4-kinase family.
    
 
 0.571
MNX1
Motor neuron and pancreas homeobox protein 1.
      
 0.563
MLXIPL
Carbohydrate-responsive element-binding protein.
      
 0.562
CHEK2
Serine/threonine-protein kinase Chk2 isoform B.
   
 
 0.541
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.514
RFXAP
Regulatory factor X-associated protein.
    
 
 0.452
FEV
Protein FEV.
   
  
 0.423
CCNK
Cyclin-K; Belongs to the cyclin family.
   
  
 0.419
PAX4
Paired box protein Pax-4.
   
  
 0.417
RFXANK
DNA-binding protein RFXANK.
    
 
 0.407
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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