Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CMPK1UMP-CMP kinase isoform B; Belongs to the adenylate kinase family. (235 aa)    
Predicted Functional Partners:
CMPK2
UMP-CMP kinase 2, mitochondrial.
    
 0.979
UMPS
Uridine 5'-monophosphate synthase.
   
 0.971
UCK2
Uridine-cytidine kinase; Belongs to the uridine kinase family.
  
 
 0.965
NME4
Nucleoside diphosphate kinase.
  
 0.963
RRM1
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
 0.957
UCK1
Uridine-cytidine kinase; Belongs to the uridine kinase family.
  
 
 0.955
AK9
Adenylate kinase 9.
   
 0.944
NME7
Nucleoside diphosphate kinase 7; Belongs to the NDK family.
  
 0.941
RRM2B-2
Uncharacterized protein.
    
 0.941
RRM2B
Ribonucleoside-diphosphate reductase subunit M2 B.
    
 0.941
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (12%) [HD]