Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRC8BUncharacterized protein. (266 aa)    
Predicted Functional Partners:
LRRC8A
Pannexin_like domain-containing protein.
    
 0.991
Y1Q_0007547
Uncharacterized protein.
    
  0.933
LRRC8C-2
Pannexin_like domain-containing protein.
    
 0.910
LRRC8C
Volume-regulated anion channel subunit LRRC8C.
  
 
 
0.819
LRRD1
Leucine-rich repeat and death domain-containing protein 1.
  
 
  0.803
LRRIQ4
Leucine-rich repeat and IQ domain-containing protein 4.
  
 
  0.798
NPEPPS
Aminopeptidase.
    
  0.664
CCBL2
Kynurenine--oxoglutarate transaminase 3 isoform B.
      
 0.643
CCBL1
Kynurenine--oxoglutarate transaminase 1.
      
 0.643
DHRS4
Dehydrogenase/reductase SDR family member 4.
    
 
 0.559
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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