STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAPGEF2Rap guanine nucleotide exchange factor 2 isoform A. (1655 aa)    
Predicted Functional Partners:
F11R
Junctional adhesion molecule A.
     
 0.939
PTPN20
Tyrosine-protein phosphatase non-receptor type 20 isoform A.
    
 0.642
PTPN13
Tyrosine-protein phosphatase non-receptor type 13 isoform C.
    
 0.642
MRAS
Ras-related protein M-Ras.
    
 0.596
RAPGEF2-2
Uncharacterized protein.
  
 
0.579
CRK
Adapter molecule crk.
    
 0.564
GRAP
GRB2-related adapter protein.
   
 0.543
GRB2
Growth factor receptor-bound protein 2.
   
 0.543
GRAP2
GRB2-related adapter protein 2.
   
 0.543
GTF2H4
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
 
      0.534
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.