STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S100A11Protein S100; Belongs to the S-100 family. (120 aa)    
Predicted Functional Partners:
ANXA1
Annexin.
   
 0.747
NAA50-1
N-alpha-acetyltransferase 50 isoform B.
    
 
 0.676
SLAMF8
SLAM family member 8.
   
 0.603
AP2A2-2
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
    
  0.597
PGLYRP3
Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity.
     
 0.589
Y1Q_0023041
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
  0.559
AP2M1
AP-2 complex subunit mu isoform B; Belongs to the peptidase M10A family.
    
  0.559
S100A9
Protein S100; Belongs to the S-100 family.
     
0.532
BORA
Protein aurora borealis.
     
 0.528
S100A6
Protein S100; Belongs to the S-100 family.
   
 
 0.519
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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