STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CSNK1ECasein kinase I isoform B; Belongs to the protein kinase superfamily. (446 aa)    
Predicted Functional Partners:
LTV1
LTV1-like protein.
    
 0.946
PRKACB
cAMP-dependent protein kinase catalytic subunit beta isoform C; Belongs to the protein kinase superfamily.
   
 
0.929
Y1Q_0006499
Uncharacterized protein; Belongs to the protein kinase superfamily.
   
 
0.923
SMO
Smoothened-like protein; Belongs to the G-protein coupled receptor Fz/Smo family.
    
  0.905
GJA1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
  0.904
GRK2
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
     
  0.900
CRY1
Cryptochrome 4.
    
 0.900
ADRBK1
G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
     
  0.900
BYSL
Bystin.
    
 0.888
RIOK2
Serine/threonine-protein kinase RIO2.
    
 0.876
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (28%) [HD]