STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCSK5Proprotein convertase subtilisin/kexin type 5 isoform B; Belongs to the peptidase S8 family. (1791 aa)    
Predicted Functional Partners:
Y1Q_0012629
S8_pro-domain domain-containing protein.
 
      0.730
SCG2
Secretogranin-2.
   
  
 0.613
POMC
Pro-opiomelanocortin.
     
 0.471
Y1Q_0000589
LRRNT domain-containing protein.
   
 0.465
RXFP1
Relaxin receptor 1 isoform A.
   
 0.465
Y1Q_0015620
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
 0.465
RXFP1-2
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
 0.465
LGR5
Uncharacterized protein.
   
 0.465
Y1Q_0007014
Repressor of RNA polymerase III transcription MAF1-like protein.
      
 0.459
TGFB1
TGF_BETA_2 domain-containing protein.
    
 0.453
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.