STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLGDNA polymerase subunit gamma-1. (1201 aa)    
Predicted Functional Partners:
POLG2
DNA polymerase subunit gamma-2, mitochondrial.
   
 
 0.954
TFAM
Transcription factor A, mitochondrial.
   
 
 0.800
GARS
Glycine--tRNA ligase.
   
 
 0.783
SSBP1
Single-stranded DNA-binding protein, mitochondrial.
   
 
 0.737
DNA2
DNA replication ATP-dependent helicase/nuclease DNA2.
   
  
 0.735
Y1Q_0019953
Helicase ATP-binding domain-containing protein.
   
 
 0.715
FANCM-1
Fanconi anemia group M protein isoform B.
   
 
 0.715
PEO1
Twinkle protein, mitochondrial.
   
  
 0.708
POLRMT
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
   
  
 0.689
TPI1
Triosephosphate isomerase.
    
 0.678
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.