STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC49Leucine-rich repeat-containing protein 49. (767 aa)    
Predicted Functional Partners:
TPGS1
Tubulin polyglutamylase complex subunit 1.
    
 0.980
TTLL1
Putative tubulin polyglutamylase TTLL1.
   
 0.978
TPGS2
Tubulin polyglutamylase complex subunit 2.
    
 0.976
Y1Q_0002275
DUF3342 domain-containing protein.
    
   0.930
TBC1D19
TBC1 domain family member 19 isoform B.
   
   0.860
EIF3F
Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
    
  0.851
TTL
Tubulin--tyrosine ligase.
   
 0.705
NME8
Thioredoxin domain-containing protein 3 isoform B.
    
 0.614
CLEC5AL
C-type lectin domain family 5 member A isoform A.
    
 0.595
CCDC148
Coiled-coil domain-containing protein 148 isoform B.
      
 0.583
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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