Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SRGAP2-2Uncharacterized protein. (1074 aa)    
Predicted Functional Partners:
ITSN1
Intersectin-1.
   
 0.734
TMEM5-1
Transmembrane protein 5 isoform B.
      
 0.715
ATAD2B
ATPase family AAA domain-containing protein 2B.
   
  
 0.682
PLXNA3
Sema domain-containing protein.
      
 0.625
ITSN1-2
Uncharacterized protein.
   
 0.576
RHOU
Rho-related GTP-binding protein RhoU.
    
 0.522
GAS7
Growth arrest-specific protein 7 isoform A.
    
 0.513
CDC42
Cell division control 42-like protein.
    
 0.513
HAUS8
HAUS augmin-like complex subunit 8.
      
 0.491
NCKIPSD
NCK-interacting protein with SH3 domain.
    
 
 0.487
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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