STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRGAP2-2Uncharacterized protein. (1074 aa)    
Predicted Functional Partners:
ITSN1
Intersectin-1.
   
0.858
ITSN1-2
Uncharacterized protein.
   
 0.705
TMEM5-1
Transmembrane protein 5 isoform B.
      
 0.671
GAS7
Growth arrest-specific protein 7 isoform A.
    
 0.622
ATAD2B
ATPase family AAA domain-containing protein 2B.
   
  
 0.607
PLXNA3
Sema domain-containing protein.
     
 0.576
WAS
Wiskott-Aldrich syndrome protein.
   
 0.542
WASL
Neural Wiskott-Aldrich syndrome protein.
   
 0.542
Y1Q_0000201
Shootin-1-like.
   
 0.527
TSEN2
tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...]
    
   0.517
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.