STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NUAK2Protein kinase domain-containing protein. (615 aa)    
Predicted Functional Partners:
STK11
Serine/threonine-protein kinase STK11; Belongs to the protein kinase superfamily.
  
 
0.673
BYSL
Bystin.
      
 0.491
ARHGEF17
Rho guanine nucleotide exchange factor 17 isoform A.
      
 0.468
MED20
Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.408
PTPN14
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily.
      
 0.404
PLEKHH3-2
Uncharacterized protein.
   
  
 0.403
USP44
Ubiquitin carboxyl-terminal hydrolase.
      
 0.400
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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