Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IKBKEUncharacterized protein. (1096 aa)    
Predicted Functional Partners:
IRF3
Interferon regulatory factor 3 isoform B.
    
 0.995
TMEM173
Stimulator of interferon genes protein.
   
 0.994
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.993
TANK
TRAF family member-associated NF-kappa-B activator.
   
 0.992
IRF7
Interferon regulatory factor 7.
   
 0.981
CYLD
Uncharacterized protein.
    
 0.973
CYLDL
Ubiquitin carboxyl-terminal hydrolase CYLD-like; Belongs to the peptidase C19 family.
    
 0.973
Y1Q_0010619
Ubiquitin carboxyl-terminal hydrolase CYLD; Belongs to the peptidase C19 family.
    
 0.962
ZBP1
Z-DNA-binding protein 1.
    
 0.954
SIKE1-1
Suppressor of IKBKE 1 isoform A.
    
 0.952
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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