STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPTBN1-2Spectrin beta chain; Belongs to the spectrin family. (2362 aa)    
Predicted Functional Partners:
SPTA1
Spectrin alpha chain, erythrocytic 1 isoform B.
   
0.823
ITSN1
Intersectin-1.
     
 0.627
TPRN
Taperin.
      
 0.585
BAIAP2L2
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2.
      
 0.559
TRIOBP
TRIO and F-actin-binding protein-like.
   
 
 0.558
MYO6
Unconventional myosin-VI isoform A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
     
 0.538
CLIC5
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
     
 0.503
FSCN2
Fascin-2.
     
 0.499
XIRP2
Xin actin-binding repeat-containing protein 2 isoform A.
    
 0.487
IQCE
IQ domain-containing protein E.
     
 0.471
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.