STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK2-2Non-specific serine/threonine protein kinase. (741 aa)    
Predicted Functional Partners:
CDC42
Cell division control 42-like protein.
   
 0.993
RAC2
Uncharacterized protein.
   
 0.979
NCK2
Cytoplasmic protein NCK2.
    
 0.979
ARHGEF6-2
Uncharacterized protein.
    
 0.976
ARHGEF6
Rho guanine nucleotide exchange factor 6 isoform B.
    
 0.976
PAK2
Non-specific serine/threonine protein kinase.
  
 
0.964
LIMK2
LIM domain kinase 2.
    
0.952
BRAF
Serine/threonine-protein kinase B-raf.
    
0.942
GNG12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
     
  0.940
Y1Q_0018386
Myosin light chain kinase, smooth muscle-like.
  
 
0.939
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.