STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SESN1-2Uncharacterized protein. (481 aa)    
Predicted Functional Partners:
WDR24
WD repeat-containing protein 24.
    
 0.782
DEPDC5
DEP domain-containing protein 5 isoform B.
    
 0.750
NPRL2
Nitrogen permease regulator 2-like protein.
    
 0.746
NPRL3
Nitrogen permease regulator 3-like protein isoform C.
    
 0.726
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.690
KPTN
Kaptin.
     
 0.684
ITFG2
Integrin-alpha FG-GAP repeat-containing protein 2.
     
 0.684
SEH1L
Nucleoporin SEH1; Belongs to the WD repeat SEC13 family.
     
 0.680
CUL3
Cullin-3; Belongs to the cullin family.
     
 0.652
MIOS
WD repeat-containing protein mio.
    
 0.649
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
Server load: low (30%) [HD]