STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSD17B617-beta-hydroxysteroid dehydrogenase type 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)    
Predicted Functional Partners:
DHRS11
Dehydrogenase/reductase SDR family member 11; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.936
HSD17B8
Estradiol 17-beta-dehydrogenase 8.
  
 
 0.931
ALDH1A3
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.910
CYP26A1
Cytochrome P450 26A1; Belongs to the cytochrome P450 family.
   
 
 0.908
BCO1
Beta,beta-carotene 15,15'-monooxygenase.
     
 0.906
HSD3B2
3 beta-hydroxysteroid dehydrogenase 1.
   
 
 0.905
CYP19A1
Aromatase; Belongs to the cytochrome P450 family.
   
 
 0.905
DGAT1
O-acyltransferase.
   
 
  0.905
LRAT
Lecithin retinol acyltransferase.
     
 0.905
SRD5A2
3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)).
   
 
 0.904
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.