STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPEGStriated muscle preferentially expressed protein kinase. (849 aa)    
Predicted Functional Partners:
Y1Q_0006660
Striated muscle preferentially expressed protein kinase-like.
 
      0.900
ARHGEF2
Rho guanine nucleotide exchange factor 2.
     
 0.734
SPEGL
Striated muscle preferentially expressed protein kinase.
 
      0.669
ARHGEF11
Rho guanine nucleotide exchange factor 11 isoform C.
     
 0.618
ARHGEF11-2
Rho guanine nucleotide exchange factor 11-like.
     
 0.618
PES1
Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
 0.609
ARHGEF19
Rho guanine nucleotide exchange factor 19.
    
 0.595
FGD3
FYVE, RhoGEF and PH domain-containing protein 3.
     
 0.593
PLEKHG4B
Pleckstrin-like proteiny domain-containing family G member 4B.
      
 0.588
WDR18
WD repeat-containing protein 18.
   
 0.579
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.