SPEG protein (Alligator mississippiensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SPEG

Striated muscle preferentially expressed protein kinase. (849 aa)

Predicted Functional Partners:

Y1Q_0006660

0.900

SPEGL

0.669

WDR18

0.620

TEX10

0.591

PES1

0.573

Y1Q_0016270

0.504

Y1Q_0012020

0.438

GNL2

0.433

NOL9-1

0.421

Your Current Organism:

Alligator mississippiensis

NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNL2	NOL9-1	A0A151NFS4	A0A151LYJ1	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Polynucleotide 5'-hydroxyl-kinase NOL9 isoform B.	0.616
GNL2	PES1	A0A151NFS4	A0A151N4V6	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.991
GNL2	SPEG	A0A151NFS4	A0A151MP33	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Striated muscle preferentially expressed protein kinase.	0.433
GNL2	SPEGL	A0A151NFS4	A0A151P6Y9	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Striated muscle preferentially expressed protein kinase.	0.433
GNL2	TEX10	A0A151NFS4	A0A151PH56	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Testis-expressed sequence 10 protein isoform B.	0.969
GNL2	WDR18	A0A151NFS4	A0A151P0I2	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	WD repeat-containing protein 18.	0.980
GNL2	Y1Q_0006660	A0A151NFS4	A0A151N9A1	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Striated muscle preferentially expressed protein kinase-like.	0.433
GNL2	Y1Q_0012020	A0A151NFS4	A0A151N4T8	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Uncharacterized protein.	0.433
GNL2	Y1Q_0016270	A0A151NFS4	A0A151P7D6	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	Ig-like domain-containing protein.	0.433
NOL9-1	GNL2	A0A151LYJ1	A0A151NFS4	Polynucleotide 5'-hydroxyl-kinase NOL9 isoform B.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.616
NOL9-1	PES1	A0A151LYJ1	A0A151N4V6	Polynucleotide 5'-hydroxyl-kinase NOL9 isoform B.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.664
NOL9-1	SPEG	A0A151LYJ1	A0A151MP33	Polynucleotide 5'-hydroxyl-kinase NOL9 isoform B.	Striated muscle preferentially expressed protein kinase.	0.421
NOL9-1	SPEGL	A0A151LYJ1	A0A151P6Y9	Polynucleotide 5'-hydroxyl-kinase NOL9 isoform B.	Striated muscle preferentially expressed protein kinase.	0.421
NOL9-1	TEX10	A0A151LYJ1	A0A151PH56	Polynucleotide 5'-hydroxyl-kinase NOL9 isoform B.	Testis-expressed sequence 10 protein isoform B.	0.929
NOL9-1	WDR18	A0A151LYJ1	A0A151P0I2	Polynucleotide 5'-hydroxyl-kinase NOL9 isoform B.	WD repeat-containing protein 18.	0.979
NOL9-1	Y1Q_0006660	A0A151LYJ1	A0A151N9A1	Polynucleotide 5'-hydroxyl-kinase NOL9 isoform B.	Striated muscle preferentially expressed protein kinase-like.	0.421
NOL9-1	Y1Q_0012020	A0A151LYJ1	A0A151N4T8	Polynucleotide 5'-hydroxyl-kinase NOL9 isoform B.	Uncharacterized protein.	0.421
NOL9-1	Y1Q_0016270	A0A151LYJ1	A0A151P7D6	Polynucleotide 5'-hydroxyl-kinase NOL9 isoform B.	Ig-like domain-containing protein.	0.421
PES1	GNL2	A0A151N4V6	A0A151NFS4	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.991
PES1	NOL9-1	A0A151N4V6	A0A151LYJ1	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	Polynucleotide 5'-hydroxyl-kinase NOL9 isoform B.	0.664