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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HOPXHomeodomain-only protein. (105 aa)    
Predicted Functional Partners:
LGR5
Uncharacterized protein.
   
  
 0.560
HOMER1
Homer protein-like protein 1.
      
 0.530
LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4.
   
  
 0.478
CLIC5
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
   
  
 0.471
IGFBP5-2
IGFBP N-terminal domain-containing protein.
      
 0.467
IGFBP5
Insulin-like growth factor-binding protein 5.
      
 0.467
LRIG1
Uncharacterized protein.
      
 0.463
ZFP36L2
Tis11B_N domain-containing protein.
      
 0.426
OTP
Homeobox protein orthopedia.
      
 0.403
CELSR1
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
      
 0.401
Your Current Organism:
Alligator mississippiensis
NCBI taxonomy Id: 8496
Other names: A. mississippiensis, American alligator
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